Registration Number
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Clinical Center
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Test Candidate
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Indication
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Objective of Study
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ChiCTR1900023000
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Shanghai East Hospital of Tongji University
|
mRNA-based Personalized Cancer Vaccine
|
Advanced Malignant Solid Tumors
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To explore the safety and efficacy of personalized cancer vaccine encoding neoantigen in the treatment of advanced malignant solid tumors.
|
NCT03468244
|
Shanghai Changhai Hospital
|
mRNA-based Personalized Cancer Vaccine
|
Gastric Adenocarcinoma
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To determine the safety, tolerability and cytokinetics and efficacy of the personalized mRNA tumor vaccine in patients with advanced esophageal squamous carcinoma, gastric adenocarcinoma, pancreatic adenocarcinoma and colorectal adenocarcinoma.
|
NCT03908671
|
First Affiliated Hospital of Zhengzhou University
|
mRNA-based Personalized Cancer Vaccine
|
Esophageal Cancer, NSCLC
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To assess the safety and tolerability and efficacy of mRNA personalized tumor vaccines encoding neoantigen for unresectable or metastatic advanced esophageal and non-small cell lung cancers with standard treatment failure or no standard treatment.
|